全象學院
The Whole Elephant Institute
洪扬中国传统文化之精髓
Spread the Traditional Chinese Culture
开辟身心灵全息研究之新天地
Pave a Path of Holistic Study of Mind-Body-Spirit
The Shen Nong 神农 Labs
Interviews:
https://www.youtube.com/watch?v=fMkHQhI5hg4
https://www.youtube.com/watch?v=ov_0GzdmH6E
Medicinal Cannabis to be Studied at the Shen Nong Labs:
Resume of Dr. Lotus King Weiss:
Resume
Dr. Lotus King Weiss
Founder and President
The Whole Elephant Institute Inc.
https://www.facebook.com/lotus.weiss
https://www.linkedin.com/in/lotus-king-weiss-%E6%9D%8E%E5%A4%A9%E6%B0%B4-aa13ba23
Contact Information
Phone:
Work:
631-552-0233
Cell Phone:
347-822-5637
Work Experience
Current Position:
o Job Title
President at the Whole Elephant Institute
o Company
The Whole Elephant Institute Inc.
o Location
Flushing NY
o From
1/2005
o To
I currently work here
o Role Description
The Whole Elephant Institute is a 501c3 non-profit organization dedicated to assist the general public to learn the 5000 years of splendid divine culture of China and to pave a path of true human life science:
I am the Founder and the current President of the Whole Elephant Institute Inc..
o At the Whole Elephant Institute Inc., I have had the following Education Experience:
o 2005: Worked as a bilingual teacher at the Tianjiao Art Institute for three months (June, July and August) to teach performing arts students Chinese Language and translated for students taking dance classes.
o 2006: Worked as an Adjunct Professor at York College to teach Biology 101 to college students.
o 2007: Established the Whole Elephant Institute Community Service Center at the Flushing Mall in Flushing, Queens Borough of New York City to teach English full time at the Center. Students are from toddlers all the way to college level students as well as adults.
o 2008: Established a new community service center in an apartment building to support senior citizens as well as provide babysitting services.
o 2009: Established a new office in the Spanish Community to do public education
o 2009: Established a new office in the Korean Community to carry out public education as well as providing social services
o 2010-2012: Rescued the Korean Community Center of New York from crisis and became the CEO of this non-profit organization and therefore worked in the Korean Community to deliver public education and social services; also started to be invited into homes of Chinese families to help with children's after school tutoring education, primarily for elementary school children.
o 2012-now: initiated and carried out all required activities for the establishment of the first chain of Chinese Charter Schools in New York State: www.confuciuscharters.org; provided home-based bilingual education to children from K-12 (about 25 students);
o 2015-now: established a bilingual training center on the most popular Chinese Social Media platform: WeChat and delivered daily bilingual lectures to about 500 students for nine months, and published the lectures through websites and social media platforms and sent links daily to over 30,000 interested students.
o Past Positions
o Job Title
Principal Investigator (PI), Assistant Professor at UW
o Company
o University Of Washington; Benaroya Research Institute
o Location
Seattle WA
o From
8/1999
o To
12/2004
o Role Description
Cancer Immunology Research: fully responsible for obtaining grant funding to support research operation of the laboratory, paying salaries to research staff, design experiments, analysis of research data, writing of research papers, publication of research articles, writing of research grant proposals, giving research lectures, management of research team members, training graduate students and postdoctoral fellows, and public relationships as well as community outreach.
o Job Title
Non-exclusive consultant at Pfizer
o Company
Pfizer
o From
9/1997
o To
10/2000
o Role Description
Consultant for the Osteoporosis Group of Pfizer
o Job Title
Principle Investigator (PI); Assistant Professor at Harvard
o Company
Harvard Medical School/Massachusetts General Hospital
o Location
Boston MA
o From
1/1997
o To
7/1999
o Role Description
Head of a research laboratory responsible for research design, data analysis, research paper writing, presentation, grant writing, hiring and training of technicians and postdoctoral fellows, pediatric surgeons, and also teach students, management of laboratory personnel
o Job Title
Instructor at Harvard
o Company
Harvard Medical School, Massachusetts General Hospital
Boston MA
o From
1/1995
o To
12/1996
o Role Description
Independent research instructor position at Harvard Medical School, with training responsibilities besides
carrying out research, writing research papers and applying for grants to support research operations.
o Job Title
Consultant at Origene
o Company
Origene Technology Inc
o Location
Maryland
o From
1/1997
o To
1/1999
o Role Description
Provide advice and research protocols of the yeast two hybrid system
o Job Title
Postdoctoral Fellow at Harvard
o Company
Harvard Medical School, Massachusetts General Hospital
o Location
Boston MA
o From
2/1993
o To
12/1994
o Role Description
Research into the molecular mechanisms of a novel family of growth inhibitors, called the Transforming Growth Factor beta (TGF-beta). The work led to the novel discoveries published in Science and Cell.
o Job Title
Lecturer at NYU
o Company
New York University
o Location
New York ,NY
o From
9/1992
o To
12/1992
o Role Description
Taught Master Level Nursing Students: Subject is Pathophysiology
Education Background
o School or University
Shanghai Medical University
o From
1984
o To
1988
o Degree
M.D. Equivalent (since the program was a six year program)
o Overall Result (GPA)
3.9
o School or University
University of Florida College of Medicine
o From
1988
o To
1992
o Degree
Ph.D. in Molecular Biology, Cell Biology and Developmental Biology
o Overall Result (GPA)
3.8
Important Skills
· Frontier Modern Life Science Research: research design; data analysis, research paper writing; publication; seminar speaker; grant writing; laboratory establishment and management; training of research staff members; teaching graduate students; mentor postdoctoral fellows; all basic life science research techniques; innovation and patents;
· K-12 Chinese-English Bilingual Education: deliver bilingual education to children K-12 in listening, reading, writing, speaking of Chinese Mandarin and English; in Math, Science and Social Study; in Chinese traditional culture; in Chinese medicine; design K-12 bilingual education curricula;
· Non-Profit Organization Establishment and Management: through community outreach to identify issues of community and design non-profit organization models in the area of education, health, media, business and law; filing applications for non-profit organization and build teams and provide trainings to team members to work on the non-profit organization platform; generate resource for the non-profit organization through fund-raising and grant writing;
· Promote and Establish Chinese Charter Schools: build the Founding Board for the Chinese Charter Schools; train Board Members; carry out community outreach for the application of the Chinese Charter Schools; write applications and submit applications for the Chinese Charter Schools; fundraising efforts to support Chinese Charter Schools;
· Social Media and Websites: build websites and apply all formats of social medias to promote non-profit mission and carry out public education;
Websites
· http://www.confuciuscharters.org
· http://www.thewholeelephant.info
Grant Applications:
http://www.thewholeelephant.info/default.html
Lectureship Roles in Modern Life Science Field (Invited Presentations)
1995 P30 Reproductive Endocrine Lecture Series at the Endocrine Science Center, MGH
1995 The Scientific Advisory Committee meeting at Massachusetts General Hospital
1996 NIH, Laboratory of Chemoprevention
1996 The 1996 Gordon Research Conference
1996 Gastrointestinal Unit, Massachusetts General Hospital
1997 Endocrine Grand Rounds, Massachusetts General Hospital
1997 University of Virginia, Department of Microbiology
1997 P30 Reproductive Endocrine Lecture Series at the Endocrine Science Center, MGH
1997 Pfizer
1997 Merck
1997 Creative Biomolecules Inc.
1997 Origene Technology Inc.
1998 The TGF-beta dinner meeting at MIT, the Whitehead Institute
1998 Department of Biochemistry and Molecular Biology, The George Washington University
1998 Division of Nephrology and Hypertension, Harbor-UCLA Medical Center
1998 National Eye Institute, National Institute of Health
1998 Department of Cancer Biology, Harvard School of Public Health
1998 Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School
1998 Annual Scientific Advisory Board Review at MGH
1998 First International Conference on bone morphogenetic proteins at Zagreb, Croatia
1999 The Third International Congress on Osteoporosis, XiAn, China
2000 International Conference, Bone Morphogenetic Proteins 2000, Lake Tahoe, CA
2001 The Hope Heart Institute, Seattle, Washington
2001 FASEB Summer Research Conferences-Tucson: TGF-beta superfamily: Signaling and Development
2002 International Future Science Forum in Cambridge, UK, Cambridge University
2002 Science Forum in Boston, MA, Harvard University
2002 China Forum (HIV crisis in China), Washington DC
2002 Ground rounds, Rheumatology Department, University of Washington
2003 Invited speaker in Gordon Conference, Polyamines, Connecticut College
2004 Invited speaker at Asian Health Forum in Washington DC
2004 Invited Speaker at WSEAS Conference in Miami
2004 Invited special session host for WSEAS Conference in Greece
2004 Invited speaker at the First International Forum For Academy Members; Changsha, PR China
2006 Invited Speaker for the NYSSAMT, New York Hospital Queens, Flushing, New York
Chinese-English Bilingual Lectures:
http://www.thewholeelephant.info/2015-Chinese-Charter-Schools.html
Original Research Articles in Publication
Modern Life Science Field (Under the name of Dr. Tongwen Wang)
She JX, Boehme S, Wang T, Bonhomme F, Wakeland EK. The generation of MHC class II gene polymorphism in the genus Mus. Biological Journal of the Linnean Society. 1991; 41:141-61.
She JX, Boehme S, Wang T, Bonhomme F. Wakeland EK. Amplification of major histocompatibility complex class II gene diversity by intraexonic recombination. Proc Natl Acad Sci USA 1991; 88:453-7.
Wang T, Lewin A, Small G. A negative regulatory element controlling transcription of the gene encoding acyl-CoA oxidase in Saccharomyces cerevisiae. Nucleic Acids Research. 1992; 20:3495-500.
Bassing CH, Yingling M. Howe DJ, Wang T, He WW, Gustafson ML, Shah P, Donahoe PK, Wang X-F. A transforming growth factor beta type I receptor that signals to activate gene expression. Science 1994; 263:87-9.
Wang T, Donahoe PK, Zervos AS. Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP12. Science 1994; 265:674-6.
Wang T, Luo Y, Small GM. The POX1 gene encoding peroxisomal acyl-CoA oxidase inSaccharomyces cerevisiae is under the control of multiple regulatory elements. J Biol Chem 1994; 269:24480-5.
Wang T, Danielson PD, Li B-Y, Shah PC, Kim SD and Donahoe PK. P21ras farnesyltransferase alpha subunit in TGF-beta and activin signaling. Science 1996; 271:1120-2.
Wang T, Li B-Y, Danielson PD, Shah PC, Rockwell S, Lechleider RJ, Martin J, Manganaro T, and Donahoe PK. The immunophilin FKBP12 functions as a common inhibitor of the TGF-beta family type I receptors. Cell 1996; 86:435-44.
Donahoe PK and Wang T. Molecular Mechanisms of Mullerian Inhibiting Substance-mediated Apoptosis. Book Chapter in “Cell Dealth in Reproductive Physiology” edited by Tilly J., Strauss JF, and Tenniswood M. 1997 Springer-Verlag New York, Inc.
Kim RH, Wang D, Marti J, Huff C., Caestecker MP, Parks T., Meng X., Lechleider RJ, Wang T. and Roberts A. A novel Smad nuclear interacting protein 1 (SNIP1) suppresses p300-dependent TGF-beta signal transduction. Genes & Development 2000; 14:1605-1616.
Liu XH, Elia A, Golemis E, Farley J. and Wang T. A novel cytoplasmic signaling mechanism of Smad3 involving proteasomal degradation of HEF1. EMBO J. 2000; 19:6759-6769.
Parks, W.T., Martin,J., Frank D.B., Huff,C., Haft, C.R., de Caestecker, M.P., McNally, J.G., Reddi, A., Taylor, S.I., Roberts, A.B., Wang, T., and Lechleider, R.J. Sorting Nexin 6, a Novel SNX, Interacts with the TGF-beta Family of Serine-Threonine Kinase Receptors. J Biol Chem. 2001 276(22): 19332-9.
Guo X., Lin Y., Horbinski, C., Drahushuk, K. M., Kim I.-J., Kaplan, P. L., Lein, P., Wang T., and Higgins, D. Dendritic Growth Induced by BMP-7 requires Smad1 and proteasome activity. J Neurobiol. 2001 48(2):120-30.
Gruendler C., Lin Y. and Wang T. Proteasomal degradation of Smad1 induced by Bone Morphogenetic Proteins. J. Biol. Chem. 2001 276: 46533-46543.
Lin Y., Martin, J. Gruendler, C., Farley, J., Meng, X., Li, B.-Y.. Lechleider, R., Huff, C., Grasser, W., Kim, R., Paralkar, V., Wang, T. A novel link between the proteasome pathway and the signal transduction pathway of the Bone Morphogenetic Proteins (BMPs)
Wang T. The 26S proteasome system in the signaling pathways of TGF-beta superfamily. Front. In Bioscience 2003, 8: 1109-1127 (invited review)
Nelson B. H., Martyak, T., Thompson, L., Moon J. J. and Wang T. Uncoupling of Promitogenic and Antiapoptotic Functions of IL-2 by Smad-Dependent TGF-beta Signaling. J. Immunol. 2003, 170:5563-70.
Wang T., Zervos T. and P. K. Donahoe. The novel role of the immunophilin FKBP12 as a regulator of the TGF-beta family type I receptors. Front. In Bioscience 2004, 9: 619-631 (invited review)
Francki A., McClure T. D., Brekken, R. A, Motamed K., Murri C., Wang T. and Sage E. H. SPARC regulates TGF-beta 1-dependent signaling in primary glomerular mesangial cells. J. Cell Biochem. 2004, 91 (5):915-25
Nourry C., Maksumova L., Liu X., Mach M., Liu X., Stroschein S. L., Luo K. and Wang T. Direct interaction between APC subunits and Smad3/HEF1 complex in proteasomal degradation of HEF1. BMC Cell Biol. 2004, 16;5(1):20
Feng L., Guedes S. and Wang T. The E3 Ub ligase hItch/AIP4 in Smad3-regulated proteasomal degradation of HEF1. J Biol Chem. 2004, 279(28): 29681-90
Quan-Zhen Li, Gabriela E. Garcia, Ping Li, Richard J. Johnson, Tongwen Wang and Lili Feng. An ancient cultivation practice Falun Gong improves neutrophil functions and causes system-level gene regulation. Proceedings of the WSEAS International Conferences, Miami, 2004; 12 International Conference On Second Messengers and Phosphoproteins, Meeting abstract, THP082, page 141.
Fluri D., Rashevasky A., Nyborg J. K., and Wang T. The regulation of a transcriptional co-repressor SNIP1 via a multimeric protein complex in BMP signaling. Manuscript in preparation
Guedes S., Holzer U., Paralkar V., Grasser W., Buckner J., and Wang T. Biochemical and functional characterization of an E3 Ub ligase hItch/AIP4 as a Smad3 interactor. Manuscript in preparation
Honors and Awards
The Claflin Distinguished Scholar Award
November 1995
The first recipient for Young Mothers as distinguished scientist in Harvard Medical School/Massachusetts General Hospital
American Cancer Society Scholar
April 2002
One Million Dollar award for cancer research
Patents
Antibody to SNIP1 (#6906179)
June 2005
Abstract:
The invention provides novel compositions comprising a Smad protein and an isolated protein component of the proteasome-mediated degradation pathway. The invention also provides novel compositions comprising a Smad1 protein and a substrate for proteasome-mediated degradation. The invention also provides methods of screening for compounds that modulate the interaction between the proteins comprising these compositions. The invention also provides methods of screening for compounds that modulate the activity of the proteins comprising these compositions. The invention also provides methods of detecting proteasome-mediated degradation of novel Smad interacting proteins. A further aspect of the invention is a kit for detecting proteasome-mediated degradation of novel Smad interacting proteins. The invention also provides methods of treating diseases which are associated with aberrant levels of activity of a TGF-beta superfamily member.
Compositions and methods for modulating TGF-beta signaling (#20020076799)
June 2002
Abstract:
The invention provides novel compositions comprising a Smad protein and an isolated protein component of the proteasome-mediated degradation pathway. The invention also provides novel compositions comprising a Smad1 protein and a substrate for proteasome-mediated degradation. The invention also provides methods of screening for compounds that modulate the interaction between the proteins comprising these compositions. The invention also provides methods of screening for compounds that modulate the activity of the proteins comprising these compositions. The invention also provides methods of detecting proteasome-mediated degradation of novel Smad interacting proteins. A further aspect of the invention is a kit for detecting proteasome-mediated degradation of novel Smad interacting proteins. The invention also provides methods of treating diseases which are associated with aberrant levels of activity of a TGF-beta superfamily member.
Methods and compositions for enhancing cellular response to TGF-beta ligands (#5912224)
June 1999
Abstract: The present invention concerns the TGF-beta receptor-mediated signaling pathway. The invention is based on the unexpected finding that TGF-beta receptor-mediated signaling is inhibited by the cytoplasmic interactor FKBP12. The invention further concerns methods and pharmaceutical compositions for enhancing cellular response to TGF-beta ligands. A screening assay is also provided for identifying macrolide potentiators capable of binding FKBP12 and thereby blocking FKBP12-inhibition of TGF-beta receptor-mediated signaling.
Important Publications to Clarify the Truth of Falun Dafa (www.falundafa.org) in an effort to End the Persecution by the Chinese Communist Party
A Wake Up Call from the Microcosm
http://www.thewholeelephant.info/Publications-in-English.html
http://www.thewholeelephant.info/Publications-in-Chinese.html
May 2002
A public lecture delivered to the general public regarding the ultimate cure of cancer of humanity
Future Science: The Science of Consciousness
http://www.thewholeelephant.info/Publications-in-English.html
http://www.thewholeelephant.info/Publications-in-Chinese.html
November 2001
A lecture delivered to the general public at Oxford University; Cambridge, England.
An ancient cultivation practice Falun Gong improves neutrophil functions and causes system-level gene regulation
http://www.asianresearch.org/articles/2397.html
http://www.clearharmony.net/articles/200410/22719.html
December 2004
The paper provided importance observations on the molecular and cellular functional changes observed in Falun Gong practitioners.
An Open Remark to the Legal Community
http://www.thewholeelephant.info/Save-Sentient-Beings.html
March 2011
This article written in 2011 was to expose the severe consequence of the Chinese Communist Government's Hate Propaganda towards Falun Dafa in America and to call upon the total stop of persecution of Falun Dafa practitioners.
A Self Portrait under the name of Dr. Tongwen Wang for the general public
Born amidst the horrific “Culture Revolution” that destroyed all traditional culture and values in China, which is known as the Divine Land where people used to believe in God, Buddha and Tao, Tongwen spent most of her childhood with her grandparents in a very under-developed village called Wen Ling at the southeast part of Mainland China. There, she was immersed in the simple beauty of the nature and the innocent smiles of the villagers. The bitter hardship of the village life became the magic seasonings for the young spirit to learn the true sweetness of inner spiritual life. When school years called her back to the city, the dreams of the villagers for better life and better health went with her and gradually become part of her own. When Cancer took the life of her grandmother, the direction of her career was solidified in her heart. With a simple wish to “Cure Cancer” as a doctor, Tongwen entered the Shanghai Medical University in 1984 when China started to open her door to the Western World. However, by the end of the fourth year in the Medical School, she experienced the total helplessness, as a doctors-to-be, in face of Cancer patients. She turned her direction towards the West and was accepted into the Anatomy and Cell Biology graduate program at the University of Florida in 1988. There, Tongwen was led, by many kind hands, to enter the field, where ardent efforts are made to understand the basic physical components of life, the Cell. The reductionism-based intellectual journey began, from the human body, to organs, tissues, and finally to the level of the Cell. In choosing her thesis focus, Tongwen took one step further and decided to look at the “dance” of the molecules. Her thesis work focuses upon the gene regulation mechanisms, using yeast as a model system. Upon completion of her graduate work, Tongwen decided that she was ready to apply the knowledge she gathered to face the problem of Cancer. She then moved to Boston and started her postdoctoral training, under the direction of Dr. Patricia Donahoe at the Massachusetts General Hospital. The focus of her interest was on a family of proteins called the Transforming Growth Factor-beta family, which are critical inhibitors of cell divisions and whose abnormalities are frequently associated with Cancer. The goal of her work is to solve the molecular mysteries behind the biological functions of this powerful family of proteins. Upon delving into the intracellular dimensions and communicating with the proteins through physical instrumentations as the mediators, a story gradually unfolded. The twists and turns in every discovery she made were interwoven with the twists and turns of her life events in the world of Science and the growth of her inner spirit. A journey into the cell finally is connected with a spiritual journey into the nature of consciousness. The search outwardly for the “Cure” of Cancer is turned into a spiritual journey to search inwardly for the “Cure” of self-delusions and the shadow nature of the world we live in.